Plant, Cell and Environment, v. A perpendicular crescent force was applied to the central area of the hind limb of the animals, which was automatically stopped when the animals presented the reaction of withdrawing the paw. Interestingly, repeated ip injection of same dose of crotamine 7. Universidade Federal Rural de Pernambuco, Targeting potassium channels in cancer. 
| Uploader: | Shaktigrel |
| Date Added: | 19 August 2007 |
| File Size: | 66.80 Mb |
| Operating Systems: | Windows NT/2000/XP/2003/2003/7/8/10 MacOS 10/X |
| Downloads: | 75300 |
| Price: | Free* [*Free Regsitration Required] |
Meaning of "sunamita" in the Portuguese dictionary
CAT activity was determined through the method described by Azevedo et al. This study aimed to evaluate the responses of the antioxidant system, sugarcane martinx and the defense mechanisms of these plants to the salt stress, and identify varieties more tolerant to this stress.
Two-way ANOVA analysis was used to identify differences in muscle force and frequency among the different experimental conditions. Venkatesh M, Gowda V.
Althougth the well-known and characteristic myastenic face and other myotoxic effects of rattlesnakebite envonoming could not be attributed to crotamine action, we could demonstrate that the purified crotamine promotes positive inotropic effect of isolated skeletal muscle with some observable signs of myolysis, and can also kill the animal when injected acutelly at high concentrations.
Sur preparations neuromusculaires in situ. Naunyn Schmiedebergs Arch Pharmacol. In addition, no animal death was registered up to 48 h after the injection of any doses of VTD assayed here up to 6. Based on the results found for the control and the NaCl concentration of 50 mM, the lower the stress, the lower the activity of these enzymes, as reported by Azevedo Statistical analysis Two-way ANOVA analysis was used to identify differences in muscle force and frequency among the different experimental conditions.
Salts and all other chemicals used in this study were of the best quality available i. The variety RB presented the lowest value and, therefore, lower capacity of adaptation to stress.
Fibre type regionalisation in lower hind limb muscles of rabbit, rat and mouse, a comparative study. From serving up practical tips for cleaning out emotional debris to making the perfect cup of tea, the book also offers captivating spa cuisine recipes that are refreshingly delicious-with the added bonus of enhancing your immune system.
SUNAMITA - Definition and synonyms of sunamita in the Portuguese dictionary
Targeting potassium channels in cancer. Cytotoxic effects of crotamine are mediated through lysosomal membrane permeabilization. Environmental Impact Assessement Review, v. Similarly, TTX was able to avoid the paralysis induced by veratridine VTDonly when administered before the injection of this plant alkaloid Table 1.
Tail suspension of mouse with typical hind limb paralysis after crotamine administration. Graciela Padilla De Amador, A method for determining loss of pain sensation.
Sodium channels as targets for volatile anesthesics. For isolated diaphragm skeletal muscle preparation, male Swiss mice of 90 to days old were euthanized by cervical dislocation, and the hemi-diaphragms were dissected before the washing with Tyrode nutrient solution mM NaCl, 5 mM KCl, 1 mM MgCl 2. On the other hand, ip injection of VTD 1. At nM of crotamine about 0. Conversely, prior ip injection of VTD did not affect the hind limbs paralysis onset or animal death which occurred about 40 min determined by crotamine administered afterward Table 1.
Contractile abnormalities of mouse muscles expressing hyperkalemic periodic paralysis mutant Na V 1. Identification of crotasin, a crotamine-related gene of Crotalus durissus terrificus. It is known that the effect of salinity on plants causes loss of quality and yield, affecting plant growth through osmotic stress and toxicity caused by the excessive accumulation of salts in the leaves Siripornadulsil et al.
Enzymatic activity of three sugarcane varieties under salt stress
Published online Aug 6. Crotamine toxicity and efficacy in mouse models of melanoma. In vivo assays Open field test The open field test was used to observe the eventual time-response or gradual decrease of the skeletal muscle functioning.
Several concentrations of crotamine i. It is also possible to hypothesize that eventual intracellular effect of crotamine may occur in the muscle cells, as we have previously demonstrated for many other cell types that intracellular organelles, as the lysosomes and mitochondria, are potential targets for this toxin [ 4849 ].
The maximum force applied in mice usnamita was of about 18 g.
Higher susceptibility of fast contraction extensor digitorum longus EDL muscle to the action of crotamine compared to the slow contraction soleus muscle of mice was previously demonstrated [ 16 ]. Tropical Sunamiya Biology, v.
No comments:
Post a Comment